| Superfamily ID | Superfamily name | Number of expanded PAT | Taxonomic source | Environment distribution |
| cl00064 | Peptidase_M54 | 112 | Link | Link |
| cl00083 | HNHc (WHH) | 679 | Link | Link |
| cl00173 | VIP2 | 155 | Link | Link |
| cl00212 | microbial_Rnases (Ribonuclease) | 127 | Link | Link |
| cl00222 | Lyz-like | 378 | Link | Link |
| cl00296 | Peptidase_C39_like | 80 | Link | Link |
| cl01480 | DUF2235 | 234 | Link | Link |
| cl02411 | RES | 31 | Link | Link |
| cl02712 | PGRP | 19 | Link | Link |
| cl03449 | M35_like | 56 | Link | Link |
| cl05417 | PLA2_like | 15 | Link | Link |
| cl07564 | Cytotoxic | 221 | Link | Link |
| cl11393 | Peptidase_M14_like | 9 | Link | Link |
| cl12957 | Colicin_D | 75 | Link | Link |
| cl13178 | DUF3274 | 3 | Link | Link |
| cl13533 | Colicin_E5 | 44 | Link | Link |
| cl15289 | DUF2380 | 17 | Link | Link |
| cl16452 | Peptidase_S74 | 4 | Link | Link |
| cl16544 | TNT | 142 | Link | Link |
| cl16625 | Tae4 | 17 | Link | Link |
| cl16861 | LHH | 149 | Link | Link |
| cl16862 | AHH | 393 | Link | Link |
| cl16870 | Toxin-deaminase | 108 | Link | Link |
| cl16877 | DYW_deaminase | 5 | Link | Link |
| cl16881 | EndoU | 304 | Link | Link |
| cl19110 | CDI_toxin_EC869_like | 106 | Link | Link |
| cl21328 | Ntox17 | 32 | Link | Link |
| cl21330 | CdiA-CT_Ecl_RNase-like | 86 | Link | Link |
| cl21334 | Ntox25 | 10 | Link | Link |
| cl21341 | Ntox43 | 33 | Link | Link |
| cl21342 | Ntox46 | 29 | Link | Link |
| cl21344 | Ntox47 | 45 | Link | Link |
| cl21346 | Ntox50 | 131 | Link | Link |
| cl21405 | Ntox15 | 117 | Link | Link |
| cl21406 | CdiA-CT_Ec_tRNase | 42 | Link | Link |
| cl21407 | Ntox34 | 3 | Link | Link |
| cl21425 | Tox-ART-HYD1 | 105 | Link | Link |
| cl21427 | Tox-GHH2 | 98 | Link | Link |
| cl21428 | Tox-GHH | 41 | Link | Link |
| cl21439 | Tox-REase-3 | 20 | Link | Link |
| cl21440 | Tox-REase-5 | 41 | Link | Link |
| cl21441 | Tox-REase-7 | 97 | Link | Link |
| cl21444 | Tox-SHH | 53 | Link | Link |
| cl21446 | Tox-WTIP | 25 | Link | Link |
| cl21449 | Tox-HNH-EHHH | 203 | Link | Link |
| cl21494 | Abhydrolase | 244 | Link | Link |
| cl21614 | YkuD_like | 11 | Link | Link |
| cl22810 | halocin_C8_dom | 7 | Link | Link |
| cl24743 | DUF4923 | 4 | Link | Link |
| cl26675 | COG5529 | 96 | Link | Link |
| cl28892 | CNF1-like | 5 | Link | Link |
| cl29459 | Glucosaminidase | 13 | Link | Link |
| cl30079 | OmpA_C-like | 93 | Link | Link |
| cl33114 | PRK15244 | 4 | Link | Link |
| cl38048 | Peptidase_M23 | 31 | Link | Link |
| cl38918 | Peptidase_M15 | 24 | Link | Link |
| cl39768 | CdiA-CT_Yk_RNaseA-like | 153 | Link | Link |
| cl39967 | ADPRTs_Tse2 | 5 | Link | Link |
| cl41214 | CdiA-CT_Ec-like | 83 | Link | Link |
| cl41215 | CdiA-CT_5T87E_Ct | 42 | Link | Link |
| cl41756 | PoNe | 317 | Link | Link |
| cl41764 | CdiA-CT_Ec_Kp-like | 73 | Link | Link |
| cl41780 | CDI_toxin_Bp_tRNase-like | 165 | Link | Link |
